Are geniuses born or made?

Some minds — think Michelangelo or Albert Einstein — are so extraordinary that they change the world. The origins of such genius are unclear, but science is beginning to offer clues.

Leonardo da Vinci's 'Vitruvian Man.'
(Image credit: Public Domain)

The Mutter Museum in Philadelphia houses an array of singular medical specimens. On the lower level the fused livers of 19th-century conjoined twins Chang and Eng float in a glass vessel. Nearby, visitors can gawk at the bladder stones of Chief Justice John Marshall, and a thighbone from a Civil War soldier with the wounding bullet still in place. But there's one exhibit near the entrance that elicits unmatchable awe. You can see smudge marks left by museumgoers pressing their foreheads against the glass.

The object that fascinates them is a small wooden box containing 46 microscope slides, each displaying a slice of Albert Einstein's brain. These remnants of tissue are mesmerizing even though — or perhaps because — they reveal little about the physicist's vaunted powers of cognition. Other displays in the museum show disease and disfigurement. Einstein's brain represents potential, the ability of one exceptional mind to catapult ahead of everyone else.

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